Glossary of Terms

What Do Medical Terms in Your Reports Mean?

To help you better understand your medical documentation, we have prepared a Glossary of Terms that explains commonly used medical expressions related to epilepsy and neurological care in a way that’s clear and accessible.

absence seizure

A type of seizure characterized by a brief loss of awareness, interruption of activity, and staring.

Previously referred to as “petit mal.”

atonic seizure

A seizure that causes a sudden loss of muscle tone, often resulting in a fall to the ground.

aura

A focal ictal phenomenon — a subjective sensation that precedes a seizure.

automatism

Repetitive, stereotypical, involuntary movements that occur without conscious control.

catemenial epilepsy

Seizures that occur in relation to the menstrual cycle.

clonic

Referring to short, repetitive muscle jerks.

cognitive

Related to thinking, perception, or recognition.

DBS

A neurostimulation method used to treat epilepsy by stimulating deep brain structures.

 

drug-resistant (refractory) epilepsy

Epilepsy that does not respond to at least two appropriate anti-seizure medications or other standard treatments.

EEG

A diagnostic test that records the electrical activity of the brain.

eloquent cortex

A brain region responsible for essential functions such as movement or speech.

Avoiding this area is critical during epilepsy surgery.

epilepsy surgery

A branch of neurosurgery focused on treating epilepsy.

etiology

The origin or cause of a disease.

febrile seizures

Seizures associated with fever above 38°C in children aged approximately 6 months to 6 years.

These may predispose to later development of mesial temporal lobe epilepsy with hippocampal sclerosis.

focal cortical dysplasia (FCD)

A developmental brain abnormality and common structural cause of epilepsy.

focal seizure

A seizure originating from one hemisphere of the brain cortex; may occur with or without impaired consciousness.

generalized seizure

A seizure involving both hemispheres of the brain at onset, as evidenced by clinical features or EEG.

habitual seizure

A patient’s typical seizure pattern.

Hippocampal sclerosis / Mesial temporal sclerosis

Damage to the tissue of the temporal lobe, involving neuronal cell loss and scarring.

idiopathic

Of unknown origin.

ictal

Pertaining to or occurring during a seizure.

interictal period

The time between seizures.

ketogenic diet

A non-pharmacological treatment involving a strict high-fat, low-carbohydrate diet.

myoclonic

Sudden, brief, involuntary jerks of a muscle or group of muscles.

peri-ictal

Occurring during or immediately (within 2–3 minutes) after a seizure.

photosensitive

Having increased sensitivity to flashing or flickering light.

postictal period

The phase immediately after a seizure, often involving temporary symptoms such as confusion, weakness, or speech disturbance.

prodrome

A preictal phenomenon occurring minutes to hours before a seizure, often involving mood or cognitive changes.

refractory

Unresponsive to treatment.

rescue medication

A fast-acting treatment administered to stop a prolonged seizure and prevent status epilepticus

seizure cluster

A group of seizures occurring within a short period of time, often with increased frequency.

seizure (ictus)

A temporary (paroxysmal) event of symptoms and/or signs due to abnormal, synchronized neuronal activity in the brain.

status epilepticus

A rare, life-threatening condition where seizures last more than 5 minutes or occur in rapid succession without full recovery of consciousness in between.

syndrome

A recognizable combination of symptoms characteristic of a particular disease or condition.

symptomatogenic zone (SZ)

The brain region responsible for producing the clinical symptoms of a seizure.

tonic

Relating to sustained muscle tension or stiffness.

VNS

A neurostimulation therapy using electrical impulses delivered to the vagus nerve in the neck to treat epilepsy.